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VELPANAT

Natco Pharma .Ltd company is the manfacture of this drug. Velpanat is a type of class of antiviral drugs that inhibits hepatitis C virus (HCV) from reproduction in the body. Velpanat is combined with other antiviral drugs (ribavirin )in people who suffering from cirrhosis

VELPANAT

Epclusa is the generic of Velpanat & is a combination of (velpatasvir 100mg +sofosbuvir400 mg) in fixed dose, and used in adult for the treatment of Hepatitis C virus infection .

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DESCRIPTION

Generic Name : Epclusa
Brand Name : Velpanat
Compositions : Velpatasvir and Sofosbuvir
Manufactured By : Natco Pharma .Ltd
Dosage Form : Tablets
Strength : 100 mg of Velpatasvir and 400 mg of Sofosbuvir
Packing : Pack of 28 tablets

VELPANAT

Velpanat has common dosage is 400mg, depends upon course ,response and difficulties against the drug dosage may slightily vary for the treatment. Velpanat should administrated orally in same time every day and taken with or without food

VELPANAT

Velpanat usually given 12weeks or 24weeks (depends on genotype) along with other combination antiviral drugs to treat HCV Velpanat mainly recommended for adult, In children safety and efficacy of the drug is not established.

VELPANAT

According to the weight of the patient Dose of ribavirin: <75kg:1000mg/day Bd ≥75kg: 1200mg/day Bd On the basis of haemoglobin and creatine clearance dosage of ribavirin is decreased.

OVERDOSE OCCURS

Any overdose with Velpanat , immediately seek to the emergency medical or poison control department.

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PHARMACOLOGY

INDICATIONS:

with chronic hepatitis C viral infection associated genotype I, II, III, IV, V or VI infection without cirrhosis or with compensated cirrhosis Velpanat is indicated for the treatment of patients who are suffered

"NS5B RNA-dependent RNA polymerase" is an enzyme and its action is inhibited by Sofosbuvir drug and "NS5A" is a protein and its action target by Velpatasvir.its works by reducing the level of hepatitis C virus in the body.

INDICATIONS:

Velpanat is used to treat chronic Hepatitis C infection in adults.
it fights against the infection and helps to improve immune system Easy recover of liver problem
Velpanat with ribavirin use decompensated cirrhosis.

Velpanat tablet composed of sofosbuvir 400mg and Velpatasvir 100mg, its directly helps for replication of hepatitis C virus by blocking the binding of two protein essential.Terminal excretion half life is Sofosbuvir is 25hrs and Velpatasvir is 15hrs.

SIDE EFFECTS :

Signs of allergy with Sofosbuvir and Velpatasvir seek to medical emergency.
Low heartbeat, Shortness of breathing, Low RBC-pale skin,fast heart rate.
Common effects:
Head pain ; feeling tried ; insomnia

PREGNANCY :

In animal studies its effect shown is low and no adverse effect in foetus and in human begins studies are prusing hence its probably safe to use during pregnancy. kindly consult doctor before use.

Prescription Medication Policy

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DISCLAIMER

This information should not be used to decide whether to accept this product or any other medicine. Only a health care provider is knowledge and training to decide that a medicine suitable for a specific patient. This information does not support any drug as safe, effective or approved for the treatment of any patient or health condition. It's simple a brief overview of general information about this product. It does not include all information on possible applications, indications, warnings, precautions, interactions, adverse effects or risks that may be relevant to this product. This information is not specific medical advice and does not replace information obtained from your health care provider. You should check with your health care provider for complete information about the risks and benefits of using this product.

ABOUT VELPANAT

DRUG INTERACTION :

• Velpanat used only with the combination of Ribavirin. The patients suffering from severe kidney or liver problems or depression, the drug Sofosbuvir is not recommended treatment.
• Velpanat with Acid reducing agents like Aluminium and magnesium hydroxide,
• H2 receptor antagonist like famotidine, proton pump inhibitors like Omeprazole these drugs are reduce the effect of concentration of Velpatasvir.
• Anticancer drug like topotecan, co administration is not recommended because of elevation of effect of concentration of topotecan

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ABOUT VELPANAT



DRUG CARE TO BE TAKEN: :

Consult with your doctor Before taking this Velpanat consult with your doctor. If you face any severe side effects also inform the doctor such as: Weekness, Difficulty in concentrating, Shallow breathing, Rapid heart rate, Reduce RBC.
MISSED DOSE:
Take it as soon as feasible the missed a dose if u missed it and if time arrives for next dose, then move out missed dose and continue regular schedule. Do not take extra or 2 dose at a time



PREGNANCY

In animal studies its effect shown is low and no adverse effect in foetus and in human begins studies are prusing hence its probably safe to use during pregnancy. kindly consult doctor before use.
STORE VELPANAT:
→ Keep Velpanat in its original container and label as child resistance.
→ Store in cool and dry place, incorrect storage lead to less effectiveness
→ Discard the medicine after expiry date
→ Discard the medicine by asking healthcare professional.

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